Polystyrene (PS) and chemically modified compounds in the PS family has long been used in commercial and industrial field. However, poorly understood whether nano-PS or PS microplastic nanoplastic exposure leads to disruption in fundamental cellular functions, such as proliferation, differentiation, and apoptosis. Here, we cultured the three main cell types, including mouse embryonic fibroblasts (MEFs), a mixture of nerve cells isolated from embryonic cortex and cortical astrocytes, and examined the effects of their exposure to nanoplastics PS with a diameter of 100 nm. Despite PS exposure nanoplastic not affect the viability of MEFs or astrocytes, significantly reduce the viability of nerve cells mix. Consistent with the observed effect on cell viability, apoptosis marker levels, cleaved caspase-3, which increased exclusively in nerve cell mixture. To investigate whether cells nanoplastics PS uptake into the cytoplasm, we MEFs and neurons exposed to latex beads PS neon and fluorescence monitored over time. We found that nanoplastics PS stored and accumulated in the cytoplasm with a concentration-dependent manner.
Although astrocytes do not apoptosis after exposure nanoplastics PS, they undergo reactive astrocytosis, with elevated levels of lipocalin-2 and pro-inflammatory cytokines. Therefore, our findings suggest that the susceptibility of cells to the deposition and accumulation nanoplastics PS in the cytoplasm depending on the cell type. Furthermore, based on our data from primary cells derived from mouse brain, we suggest that reactive astrocytosis may contribute to neuronal apoptosis seen in the damaged neurons with nanoplastics PS accumulates in the cells of the body.
Primary bone adult T-cell lymphoma with multiple bone lesions painful and debilitating osteolysis: a case report
Only there are some reports of major adult T-cell lymphoma / leukemia (ATL) in the bone. This is a case report of a patient 75 years initially reported some bone pain associated with osteolytic ATL. Patients developed spontaneous chest / back pain and visited a local hospital. Laboratory tests showed high levels of alkaline phosphatase (ALP), and computed tomography (CT) revealed a bone lesion with osteolysis. Although multiple myeloma was initially suspected, the results of bone marrow aspiration and biopsy of bone inconsistent.
After he was referred to our hospital, mild hypercalcemia (10.4 mg / dL) with normal lower intact parathyroid hormone (PTH) (27 pg / mL), low parathyroid hormone-related protein (PTHrP), and increased 1,25- dihydroxy vitamin D (1,25OH2D) levels (136 pg / mL) to narrow the differential diagnosis lymphomatous and granulomatous disease, and subsequently, high serum soluble IL-2 receptor (3450 U / mL) and the cells of interest are recognized in peripheral blood samples suggesting the involvement of ATL. Finally, reevaluation of iliac bone biopsy samples for histological diagnosis prompted us ATL infiltration in the bone.
Two subsequent courses of chemotherapy in addition to denosumab resulted in a partial metabolic response of interest shown in positron emission fluorine-18-fluorodeoxyglucose tomography / computed tomography (18F-FDG PET / CT). Although very rare, bone involvement ATL can be used for differential diagnosis to local osteolytic bone pain in addition to multiple myeloma and metastatic bone disease.
Fatty-acid-induced FABP5 / HIF-1 reprograms the metabolism of lipids and increase the liver cancer cell proliferation
Hypoxia-inducible factor-1 alpha (HIF-1α) is a transcription factor essential for the survival of cancer cells. Reprogramming of lipid metabolism has emerged as a hallmark of cancer, but the relevance of HIF-1α to this process have remained elusive. In this study, we profile HIF-1α-interacting protein using proteomic analysis and identify the fatty acid binding protein 5 (FABP5) as a partner of the binding of HIF-1α-critical. In hepatocellular carcinoma (HCC) network, both FABP5 and HIF-1α regulated, and their expression levels associated with a poor prognosis. FABP5 increases the activity of HIF-1α by promoting the synthesis of HIF-1α while disturbing FIH / HIF-1α interaction at the same time. oleic-acid treatment activate FABP5 / HIF-1α axis, thus increasing lipid accumulation and proliferation of cells in HCC cells. Our results indicate that the fatty acid-induced upregulation drive FABP5 HCC development through HIF-1-driven lipid metabolism reprogramming.
Behavioral Observation of Epithelial Cells in Nasal Septal Closure During Primary Palate in Mice
Epithelial fusion is very important in palatogenesis and incomplete fusion results in various types of facial cleft, depending on the area that failed to fuse. In palatogenesis mammals, the secondary palatal bilateral fuse in the middle of the face to form the secondary palate. Then, the dorsal side of the secondary palatal shelves fuse with the nasal septum to complete palatogenesis. Importantly, the anterior border of the secondary palatal shelves fuse with the main ceiling, which is located on the border of the anterior and ventral nasal septum. While many studies have investigated the mechanism of fusion between secondary palatal shelves, very little is known about how to touch the ceiling fuse with the primary and secondary palatal shelves. In this study, we investigated the possible behavior of epithelial cells on the surface of the main ceiling using explant culture palatal K14-GFP mice.
Immortalized Mouse Oral Keratinocytes (IMOK) |
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| T0855 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Immortalized Normal Human Oral Mucosal Keratinocytes |
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| T0768 | ABM | 5x10^5 cells / 1.0 ml | EUR 3950 |
Immortalized Human Oral Gingival Keratinocytes (HPV-16 GM) |
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| T0717 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Primary Mouse Neonatal Epidermal Keratinocytes (NEK) |
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| CSI075Mu01 | Cloud-Clone | 5X10^5 | EUR 940 |
Primary Rabbit Neonatal Epidermal Keratinocytes (NEK) |
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| CSI075Rb01 | Cloud-Clone | 5X10^5 | EUR 1360 |
Human Keratinocytes |
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| ALHE41 | Alphabioregen | 1ml frozen Vial | EUR 620 |
Human Skin PrimaCell™1: Normal Epidermal Keratinocytes |
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| 2-96101 | CHI Scientific | 1 Kit | EUR 1132.11 |
Human Keratinocytes, Adult |
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| ABC-TC3030 | AcceGen | 1 vial | Ask for price |
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Description: Gentaur epidermal keratinocytes are available from adult and neonatal donor tissue and are provided at the earliest passage without the use of a murine feeder layer. Keratinocytes are available from donors of varying ages, genders, and diabetes status. Donor matched epidermal keratinocytes, dermal fibroblasts, melanocytes and subcutaneous preadipocytes are available. |
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Human keratinocytes, Dermis |
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| ABC-TC3659 | AcceGen | 1 vial | Ask for price |
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Description: The HKER-D cultures are produced on the base of human tissues. The HKER-D are isolated according to known procedures. Then primary cultures are produced. |
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Human Dermal Keratinocytes |
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| cAP-0212 | Angio Proteomie | 1Frozen Vial | EUR 475.2 |
Human keratinocytes, Foreskin |
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| ABC-TC3660 | AcceGen | 1 vial | Ask for price |
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Description: The HKER-F cultures are produced on the base of human tissues. The HKER-F are isolated according to known procedures. Then primary cultures are produced. After further culturing, the HKER-F are frozen in a computer controlled freezing unit. |
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Human Gingival Keratinocytes |
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| cAP-0216 | Angio Proteomie | 1Frozen Vial | EUR 643.5 |
Human Caucasian dysplastic oral keratinocyte |
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| P0020024 | Addexbio | One Frozen vial | EUR 995 |
Human Embryo PrimaCell™3: Normal Fetal Epidermal Keratinocytes |
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| 2-96052 | CHI Scientific | 1 Kit | EUR 1228.5 |
Human Corneal Keratinocytes (HCK) |
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| P0029012 | Addexbio | One Frozen vial | EUR 650 |
Human New Borns PrimaCell™: Normal New Born Epidermal Keratinocytes |
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| 2-96093 | CHI Scientific | 1 Kit | EUR 1228.5 |
Human iPSC-derived Keratinocytes |
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| CSC-00840L | Creative Bioarray | One Frozen vial | Ask for price |
Human Skin PrimaCell™1: Normal Epidermal Keratinocytes Growth Medium |
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| 9-46101 | CHI Scientific | 5 x 100 ml | EUR 151.2 |
Human Epidermal Keratinocytes, Adult |
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| ABC-TC3604 | AcceGen | 1 vial | Ask for price |
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Description: The epithelial layer of the skin provides an essential function as a protective barrier against insult from the outside environment. The major cell type in this layer is keratinocytes which consists around 85% of living epidermal cells. Keratinocytes are the cells of stratified squamous epithelia. It is so named because its most abundant protein is keratin. Keratinocyte divide and are thus generated in the basal layer of the epidermis; this division is followed by a programmed death as they produce keratin and move up to the surface of the epidermis. Keratinocyte proliferation, differentiation, and apoptosis are complex and carefully choreographed processes. Besides the protective function, keratinocytes also play a central role in tissue homeostasis, wound healing, cancers, and skin-based gene-therapy. Human keratinocytes express adhesion molecules and cytokines indicating their participation in skin innate immunity and homeostasis in vivo. HEK-a from Gentaur Research Laboratories are isolated from adult human epidermal tissue. HEK-a are cryopreserved on primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HEK-a are characterized by immunofluorescent method with antibodies to cytokeratine-18 and -19. HEK-a are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HEK-a are guaranteed to further expand for 15 population doublings in the condition provided by Gentaur Research Laboratories. |
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Human Epidermal Keratinocytes, Fetal |
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| ABC-TC3605 | AcceGen | 1 vial | Ask for price |
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Description: The epithelial layer of the skin provides an essential function as a protective barrier against insult from the outside environment. The major cell type in this layer is keratinocytes which consists around 85% of living epidermal cells. Keratinocytes are the cells of stratified squamous epithelia. It is so named because its most abundant protein is keratin. Keratinocyte divide and are thus generated in the basal layer of the epidermis; this division is followed by a programmed death as they produce keratin and move up to the surface of the epidermis. Keratinocyte proliferation, differentiation, and apoptosis are complex and carefully choreographed processes. Besides the protective function, keratinocytes also play a central role in tissue homeostasis, wound healing, cancers, and skin-based gene-therapy. Human keratinocytes express adhesion molecules and cytokines indicating their participation in skin innate immunity and homeostasis in vivo. HEK-f from Gentaur Research Laboratories are isolated from fetal human epidermal tissue. HEK-f are cryopreserved on primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HEK-f are characterized by immunofluorescent method with antibodies to cytokeratine-18 and -19. HEK-f are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HEK-f are guaranteed to further expand for 15 population doublings in the condition provided by Gentaur Research Laboratories. |
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Human Hair Follicular Keratinocytes |
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| ABC-TC3637 | AcceGen | 1 vial | Ask for price |
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Description: Hair follicles are self-renewing structures that cycle and reconstitute themselves throughout life because they contain keratinocyte stem cells. The interplay between keratinocytes and underlying mesenchyme are critical for hair follicle morphogenesis and cycling. Several key developmental pathways are involved in determining follicular keratinocyte fate as well as the differentiation into several distinct cellular layers of the follicle during the growth phase of hair. Studies indicate that follicular keratinocytes are distinct from epidermal keratinocytes in proliferative capacity and CD34 expression.HHFK from Gentaur Research Laboratories are isolated from human hair follicles. HHFK are cryopreserved on primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HHFK are characterized by immunofluorescent method with antibodies to cytokeratines. HHFK are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HHFK are guaranteed to further expand for 15 population doublings in the condition provided by Gentaur Research Laboratories. |
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Human Keratinocytes, Pooled Neonatal |
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| ABC-TC3662 | AcceGen | 1 vial | Ask for price |
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Description: Gentaur epidermal keratinocytes are available from adult and neonatal donor tissue and are provided at the earliest passage without the use of a murine feeder layer. Keratinocytes are available from donors of varying ages, genders, and diabetes status. Donor matched epidermal keratinocytes, dermal fibroblasts, melanocytes and subcutaneous preadipocytes are available. |
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Human Hair Follicular Keratinocytes |
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| CSC-7776W | Creative Bioarray | One Frozen vial | Ask for price |
Human Epidermal Keratinocytes, Foetal |
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| ABC-TC3603 | AcceGen | 1 vial | Ask for price |
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Description: Human Epidermal Keratinocytes (HEK) are primary cells isolated from normal human neonatal foreskin or adult skin. They are cryopreserved at the end of primary culture and can be cultured and propagated at least 16 population doublings. |
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Human Dermal Epidermal Keratinocytes |
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| CSC-C9225J | Creative Bioarray | One Frozen vial | Ask for price |
Normal Human Epidermal Keratinocytes |
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| CSC-7640W | Creative Bioarray | One Frozen vial | Ask for price |
Human Epidermal Keratinocytes, Neonatal |
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| ABC-TC3606 | AcceGen | 1 vial | Ask for price |
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Description: The epithelial layer of the skin provides an essential function as a protective barrier against insult from the outside environment. The major cell type in this layer is keratinocytes which consists around 85% of living epidermal cells. Keratinocytes are the cells of stratified squamous epithelia. It is so named because its most abundant protein is keratin. Keratinocyte divide and are thus generated in the basal layer of the epidermis; this division is followed by a programmed death as they produce keratin and move up to the surface of the epidermis. Keratinocyte proliferation, differentiation, and apoptosis are complex and carefully choreographed processes. Besides the protective function, keratinocytes also play a central role in tissue homeostasis, wound healing, cancers, and skin-based gene-therapy. Human keratinocytes express adhesion molecules and cytokines indicating their participation in skin innate immunity and homeostasis in vivo. HEK-n from Gentaur Research Laboratories are isolated from neonate human epidermal tissue. HEK-n are cryopreserved on primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HEK-n are characterized by immunofluorescent method with antibodies to cytokeratine-18 and -19. HEK-n are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HEK-n are guaranteed to further expand for 15 population doublings in the condition provided by Gentaur Research Laboratories. |
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Human Neonatal Epidermal Keratinocytes |
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| ABC-TC3985 | AcceGen | 1 vial | Ask for price |
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Description: Neonatal Human Epidermal Keratinocytes (NHEK) are cultured by first, isolating the keratinocytes from the epidermis of the neonatal skin and then, establishing a primary keratinocyte culture. Upon completion of the primary culture, the cells are harvested, aliquoted into individual vials, and placed in liquid nitrogen storage until shipment. This product has been thoroughly tested and found to be free of the HIV Type I, Viral Hepatitis Type B and C, mycoplasma, bacteria, yeast, and fungi. |
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Immortalized Human Dermal Keratinocytes |
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| CSC-I2035Z | Creative Bioarray | One Frozen vial | Ask for price |
Human Embryo PrimaCell™3: Normal Fetal Epidermal Keratinocytes Growth Medium |
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| 9-46052 | CHI Scientific | 5 x 100 ml | EUR 151.2 |
Immortalized Human Epidermal Keratinocytes |
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| T0345 | ABM | 1x106 cells / 1.0 ml | EUR 3950 |
Rat Skin PrimaCell™1: Normal Epidermal Keratinocytes |
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| 2-82582 | CHI Scientific | 1 Kit | EUR 1039.5 |
Human Keratinocytes, Adult, Diabetic Donor |
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| ABC-TC3031 | AcceGen | 1 vial | Ask for price |
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Description: Gentaur epidermal keratinocytes are available from adult and neonatal donor tissue and are provided at the earliest passage without the use of a murine feeder layer. Keratinocytes are available from donors of varying ages, genders, and diabetes status. Donor matched epidermal keratinocytes, dermal fibroblasts, melanocytes and subcutaneous preadipocytes are available. |
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Human Keratinocytes, Neonatal, Single Donor |
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| ABC-TC3661 | AcceGen | 1 vial | Ask for price |
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Description: Gentaur epidermal keratinocytes are available from adult and neonatal donor tissue and are provided at the earliest passage without the use of a murine feeder layer. Keratinocytes are available from donors of varying ages, genders, and diabetes status. Donor matched epidermal keratinocytes, dermal fibroblasts, melanocytes and subcutaneous preadipocytes are available. |
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Human New Borns PrimaCell™: Normal New Born Epidermal Keratinocytes Growth Medium |
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| 9-46093 | CHI Scientific | 5 x 100 ml | EUR 151.2 |
Mouse Skin PrimaCell™1: Normal Epidermal Keratinocytes |
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| 2-82085 | CHI Scientific | 1 Kit | EUR 943.11 |
Human Epidermal Keratinocytes, Adult, Pooled |
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| ABC-TC3976 | AcceGen | 1 vial | Ask for price |
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Description: Epidermal keratinocytes represent the major cell type of the epidermis, making up about 90% of the cells. They originate in the stratum basale and undergo gradual differentiation including profound morphological changes during their shift to the stratum corneum. In the stratum corneum, the final barrierlayer of the skin, keratinocytes are found as nucleus-free, flat, and highly keratinized squamous cells. Gentaur offers a range of Normal Human Epidermal Keratinocytes (NHEK) from single donors or pooled donors produced at Promo- Cell’s cell culture facility. The cells are isolated from juvenile foreskin or from adult normal human tissue from different locations, e.g. face, breast, abdomen, and thighs. Shortly after isolation, all Gentaur Normal Human Epidermal Keratinocytes are cryopreserved at passage 2 (P2) using Gentaur's proprietary, serum-free freezing medium, Cryo-SFM. Each cryo vial contains more than 500,000 viable cells after thawing. Proliferating cell cultures are made from 500,000 cryopreserved cells that have been thawed and cultured for three days at Gentaur. |
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Human Epidermal Keratinocytes, Neonatal, Pooled |
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| ABC-TC3961 | AcceGen | 1 vial | Ask for price |
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Description: Normal Human Epidermal Keratinocytes (NHEK) have longer guaranteed life spans than KGM or KGM-2 cells with ≥18 total population doublings for Adult cells and ≥20 population doublings for neonatal cells. |
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Immortalized Human Corneal Keratinocytes (IHCK) |
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| T0579 | ABM | 1x106 cells / 1.0 ml | EUR 3950 |
Immortalized Human Epidermal Keratinocytes (SIK) |
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| T0770 | ABM | 1x106 cells / 1.0 ml | EUR 3950 |
Human Epidermal Keratinocytes, 10-Donor Pool |
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| ABC-TC3980 | AcceGen | 1 vial | Ask for price |
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Description: Normal Human Epidermal Keratinocytes (HEK), when grown in LIDer K Medium, provide an ideal serum-free culture model, for the study of wound healing, toxicology or epithelial biology. When in need of multiple keratinocyte cell lots, our HEK, 10-donor pool offers a wide range of donor demographics for research at an economical price. All HEK are quality tested in LIDer K Medium to ensure optimal serum-free growth over a period of at least 15 population doublings at rates equal to or greater than serum-supplemented medium. Our HEK need not be exposed to antimicrobials or phenol red when cultured in LIDer medium; an advantage since these supplements can cause cell stress and "masking effects" that may negatively impact experimental result.Cell Features:HEKn are cryopreserved as primary cells. Cells are isolated from neonatal human foreskin and expanded once in culture vessels before cryopreservation.HEKa are cryopreserved as primary cells. Cells are isolated from adult human skin and expanded once in culture vessels before cryopreservation.HEK can be grown without serum, phenol red or antimicrobials when cultured in DermaLife medium.HEK are extensively tested for quality and optimal performance.Gentaur guarantees performance and quality. |
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SV40-Human Dermal Keratinocytes |
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| cAP-0212-SV40 | Angio Proteomie | 1Frozen Vial | EUR 5049 |
Rat Embryo PrimaCell™3: Normal Fetal Epidermal Keratinocytes |
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| 2-82533 | CHI Scientific | 1 Kit | EUR 1039.5 |
hTert-Human Dermal Keratinocytes |
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| cAP-0212-hTert | Angio Proteomie | 1Frozen Vial | EUR 5049 |
Immortalized Human Epidermal Keratinocytes-SV40 |
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| CSC-I9096L | Creative Bioarray | One Frozen vial | Ask for price |
Immortalized Human Gingival Keratinocytes-hTERT |
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| CSC-I9236L | Creative Bioarray | One Frozen vial | Ask for price |
SV40-Human Gingival Keratinocytes |
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| cAP-0216-SV40 | Angio Proteomie | 1Frozen Vial | EUR 5049 |
Immortalized Human Epidermal Keratinocytes-hTERT |
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| CSC-I2104Z | Creative Bioarray | One Frozen vial | Ask for price |
Human Epidermal Keratinocytes, Adult, Single Donor |
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| ABC-TC3977 | AcceGen | 1 vial | Ask for price |
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Description: Epidermal keratinocytes represent the major cell type of the epidermis, making up about 90% of the cells. They originate in the stratum basale and undergo gradual differentiation including profound morphological changes during their shift to the stratum corneum. In the stratum corneum, the final barrierlayer of the skin, keratinocytes are found as nucleus-free, flat, and highly keratinized squamous cells. Gentaur offers a range of Normal Human Epidermal Keratinocytes (NHEK) from single donors or pooled donors produced at Promo- Cell’s cell culture facility. The cells are isolated from juvenile foreskin or from adult normal human tissue from different locations, e.g. face, breast, abdomen, and thighs. Shortly after isolation, all Gentaur Normal Human Epidermal Keratinocytes are cryopreserved at passage 2 (P2) using Gentaur's proprietary, serum-free freezing medium, Cryo-SFM. Each cryo vial contains more than 500,000 viable cells after thawing. Proliferating cell cultures are made from 500,000 cryopreserved cells that have been thawed and cultured for three days at Gentaur. |
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hTert-Human Gingival Keratinocytes |
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| cAP-0216-hTert | Angio Proteomie | 1Frozen Vial | EUR 5049 |
Mouse Embryo PrimaCell™3: Normal Fetal Epidermal Keratinocytes |
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| 2-82032 | CHI Scientific | 1 Kit | EUR 1039.5 |
Rat Epidermal Keratinocytes |
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| ABC-TC4130 | AcceGen | 1 vial | Ask for price |
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Description: Rat Epidermal Keratinocytes (REK) are derived from the skin of normal Sprague Dawley rats. They are cryopreserved at the end of primary culture. These epithelial cells proliferate well when thawed and plated from cryopreservation. |
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Rat New Borns PrimaCell™: Normal New Born Epidermal Keratinocytes |
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| 2-82575 | CHI Scientific | 1 Kit | EUR 943.11 |
Human Adult Epi. Keratinocytes-Diabetic Type II |
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| ABC-TC3481 | AcceGen | 1 vial | Ask for price |
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Description: Diseased Human Epidermal Keratinocytes (D-HEK) are isolated from human donors that have been diagnosed with diabetes type II disease. Diseased cells are grown in the same optimized media system as Normal Human Keratinocytes. |
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Mouse New Borns PrimaCell™: Normal New Born Epidermal Keratinocytes |
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| 2-82076 | CHI Scientific | 1 Kit | EUR 1039.5 |
Human HACAT Keratinocyte Cells |
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| CR1017-500 | celleng-tech | 1 vial | EUR 1000 |
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Description: Cryopreserved vial of human keratinocyte cells containing ≥ 500,000 cells |
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Rat Skin PrimaCell™1: Normal Epidermal Keratinocytes Growth Medium |
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| 9-25082 | CHI Scientific | 5 x 100 ml | EUR 122.85 |
Human Epidermal Keratinocytes, Juvenile Foreskin, Pooled |
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| ABC-TC3978 | AcceGen | 1 vial | Ask for price |
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Description: Epidermal keratinocytes represent the major cell type of the epidermis, making up about 90% of the cells. They originate in the stratum basale and undergo gradual differentiation including profound morphological changes during their shift to the stratum corneum. In the stratum corneum, the final barrierlayer of the skin, keratinocytes are found as nucleus-free, flat, and highly keratinized squamous cells. Gentaur offers a range of Normal Human Epidermal Keratinocytes (NHEK) from single donors or pooled donors produced at Promo- Cell’s cell culture facility. The cells are isolated from juvenile foreskin or from adult normal human tissue from different locations, e.g. face, breast, abdomen, and thighs. Shortly after isolation, all Gentaur Normal Human Epidermal Keratinocytes are cryopreserved at passage 2 (P2) using Gentaur's proprietary, serum-free freezing medium, Cryo-SFM. Each cryo vial contains more than 500,000 viable cells after thawing. Proliferating cell cultures are made from 500,000 cryopreserved cells that have been thawed and cultured for three days at Gentaur. |
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Immortalized Human Gingival Keratinocytes (Gie-No3B11) |
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| T0049 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Human Foreskin Keratinocytes (HFK-16E6E7) |
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| T0723 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Mouse Skin PrimaCell™1: Normal Epidermal Keratinocytes Growth Medium |
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| 9-32085 | CHI Scientific | 5 x 100 ml | EUR 122.85 |
hTert-CDK4-Human Dermal Keratinocytes |
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| cAP-0212-hTert-CDK4 | Angio Proteomie | 1Frozen Vial | EUR 6435 |
hTert-CDK4-Human Gingival Keratinocytes |
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| cAP-0216-hTert-CDK4 | Angio Proteomie | 1Frozen Vial | EUR 6435 |
Mouse Monoclonal anti-human keratinocytes |
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| hAP-0791 | Angio Proteomie | 50ug | EUR 400 |
Human Skin PrimaCell™1: Normal Epidermal Keratinocytes Growth Supplements with Serum (for 500 ml medium) |
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| 9-47101 | CHI Scientific | 1 Set | EUR 321.3 |
Rat Embryo PrimaCell™3: Normal Fetal Epidermal Keratinocytes Growth Medium |
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| 9-25033 | CHI Scientific | 5 x 100 ml | EUR 122.85 |
Mouse Embryo PrimaCell™3: Normal Fetal Epidermal Keratinocytes Growth Medium |
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| 9-32032 | CHI Scientific | 5 x 100 ml | EUR 122.85 |
Rat New Borns PrimaCell™: Normal New Born Epidermal Keratinocytes Growth Medium |
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| 9-25075 | CHI Scientific | 5 x 100 ml | EUR 122.85 |
Human Epidermal Keratinocytes, Juvenile foreskin, Single donor |
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| ABC-TC3979 | AcceGen | 1 vial | Ask for price |
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Description: Epidermal keratinocytes represent the major cell type of the epidermis, making up about 90% of the cells. They originate in the stratum basale and undergo gradual differentiation including profound morphological changes during their shift to the stratum corneum. In the stratum corneum, the final barrierlayer of the skin, keratinocytes are found as nucleus-free, flat, and highly keratinized squamous cells. Gentaur offers a range of Normal Human Epidermal Keratinocytes (NHEK) from single donors or pooled donors produced at Promo- Cell’s cell culture facility. The cells are isolated from juvenile foreskin or from adult normal human tissue from different locations, e.g. face, breast, abdomen, and thighs. Shortly after isolation, all Gentaur Normal Human Epidermal Keratinocytes are cryopreserved at passage 2 (P2) using Gentaur's proprietary, serum-free freezing medium, Cryo-SFM. Each cryo vial contains more than 500,000 viable cells after thawing. Proliferating cell cultures are made from 500,000 cryopreserved cells that have been thawed and cultured for three days at Gentaur. |
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Rat Epidermal Keratinocytes-neonate |
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| ABC-TC4131 | AcceGen | 1 vial | Ask for price |
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Description: The epithelial layer of the skin provides an essential function as a protective barrier against insult from the outside environment. The major cell type in this layer is keratinocytes which consists around 85% of living epidermal cells. |
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Mouse New Borns PrimaCell™: Normal New Born Epidermal Keratinocytes Growth Medium |
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| 9-32076 | CHI Scientific | 5 x 100 ml | EUR 122.85 |
Human Embryo PrimaCell™3: Normal Fetal Epidermal Keratinocytes Growth Supplements with Serum (for 500 ml medium) |
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| 9-47052 | CHI Scientific | 1 Set | EUR 321.3 |
C57BL/6 Mouse Epidermal Keratinocytes |
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| ABC-TC5526 | AcceGen | 1 vial | Ask for price |
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Description: C57BL/6 Mouse Primary Epidermal Keratinocytes from Gentaur are isolated from skin tissue of pathogen-free laboratory mice. C57BL/6 Mouse Primary Epidermal Keratinocytes are grown in a T25 tissue culture flask pre-coated with gelatin-based coating solution for 2 min and incubated in Gentaur's Culture Complete Growth Medium for 3-5 days. Cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 0.5x106 cells per ml and is delivered frozen. Cells can be expanded on a multiwell culture plate ready for experiments under the cell culture conditions specified by Gentaur. The method we use to isolate primary epithelial cells was developed based on a combination of established and our proprietary methods. These cells are pre-coated with EpCAM-1 (CD326) antibody, followed by the application of magnetic beads pre-coated with secondary antibody. |
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Human New Borns PrimaCell™: Normal New Born Epidermal Keratinocytes Growth Supplements with Serum (for 500 ml medium) |
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| 9-47093 | CHI Scientific | 1 Set | EUR 321.3 |
Immortalized Human Neonatal Foreskin Keratinocytes (HKc16E6/E7-II) |
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| T0726 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Human Skin Tissue Preparation Buffer 1: Normal Epidermal Keratinocytes |
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| 9-80101 | CHI Scientific | 1 x 100 ml | EUR 160.65 |
Immortalized Mouse Epidermal Keratinocytes-SV40 |
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| CSC-I2200Z | Creative Bioarray | One Frozen vial | Ask for price |
Rat Skin PrimaCell™1: Normal Epidermal Keratinocytes Growth Supplements with Serum (for 500 ml medium) |
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| 9-26082 | CHI Scientific | 1 Set | EUR 283.5 |
Immortalized Mouse Epidermal Keratinocytes (CDC25A F7) |
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| T0299 | ABM | 1x106 cells / 1.0 ml | EUR 3950 |
Immortalized Multimammate Mouse Skin Keratinocytes (Kera5) |
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| T0763 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Human Embryo Tissue Preparation Buffer 3: Normal Fetal Epidermal Keratinocytes |
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| 9-80052 | CHI Scientific | 1 x 100 ml | EUR 160.65 |
Mouse Skin PrimaCell™1: Normal Epidermal Keratinocytes Growth Supplements with Serum (for 500 ml medium) |
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| 9-33085 | CHI Scientific | 1 Set | EUR 283.5 |
Human New Borns Tissue Preparation Buffer: Normal New Born Epidermal Keratinocytes |
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| 9-80093 | CHI Scientific | 1 x 100 ml | EUR 160.65 |
Skin Dissociation System 4 (Keratinocytes), Mouse and Rat |
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| 4-20434 | CHI Scientific | ea | EUR 144.82 |
Rat Embryo PrimaCell™3: Normal Fetal Epidermal Keratinocytes Growth Supplements with Serum (for 500 ml medium) |
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| 9-26033 | CHI Scientific | 1 Set | EUR 283.5 |
Mouse Embryo PrimaCell™3: Normal Fetal Epidermal Keratinocytes Growth Supplements with Serum (for 500 ml medium) |
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| 9-33032 | CHI Scientific | 1 Set | EUR 283.5 |
Immortalized Mouse Mutant Epidermal Keratinocytes (CDC25A 8b) |
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| T0298 | ABM | 1x106 cells / 1.0 ml | EUR 3950 |
Rat New Borns PrimaCell™: Normal New Born Epidermal Keratinocytes Growth Supplements with Serum (for 500 ml medium) |
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| 9-26075 | CHI Scientific | 1 Set | EUR 283.5 |
Mouse New Borns PrimaCell™: Normal New Born Epidermal Keratinocytes Growth Supplements with Serum (for 500 ml medium) |
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| 9-33076 | CHI Scientific | 1 Set | EUR 283.5 |
Immortalized Mouse Wildtype M4+/+ Epidermal Keratinocytes |
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| T0459 | ABM | 1x106 cells / 1.0 ml | EUR 3950 |
Immortalized Mouse EGFR Mutant M4 -/- Epidermal Keratinocytes |
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| T0460 | ABM | 1x106 cells / 1.0 ml | EUR 3950 |
Immortalized Mouse EGFR Mutant M3-/- Epidermal Keratinocytes |
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| T0461 | ABM | 1x106 cells / 1.0 ml | EUR 3950 |
Rat Skin Tissue Preparation Buffer 1: Normal Epidermal Keratinocytes |
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| 9-80289 | CHI Scientific | 1 x 100 ml | EUR 132.3 |
Kprp (untagged ORF) - Rat keratinocytes proline-rich protein (Kprp), (10 ug) |
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| RN202226 | Origene Technologies GmbH | 10 µg | Ask for price |
Mouse Skin Tissue Preparation Buffer 1: Normal Epidermal Keratinocytes |
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| 9-80199 | CHI Scientific | 1 x 100 ml | EUR 160.65 |
Rat Embryo Tissue Preparation Buffer 3: Normal Fetal Epidermal Keratinocytes |
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| 9-80240 | CHI Scientific | 1 x 100 ml | EUR 132.3 |
Skin Dissociation System 1 (Dermal fibroblast and keratinocytes), Mouse and Rat |
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| 4-20431 | CHI Scientific | ea | EUR 178.86 |
Mouse Embryo Tissue Preparation Buffer 3: Normal Fetal Epidermal Keratinocytes |
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| 9-80146 | CHI Scientific | 1 x 100 ml | EUR 160.65 |
Kprp (Myc-DDK-tagged ORF) - Rat keratinocytes proline-rich protein (Kprp), (10 ug) |
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| RR202226 | Origene Technologies GmbH | 10 µg | Ask for price |
Rat New Borns Tissue Preparation Buffer: Normal New Born Epidermal Keratinocytes |
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| 9-80282 | CHI Scientific | 1 x 100 ml | EUR 132.3 |
Mouse New Borns Tissue Preparation Buffer: Normal New Born Epidermal Keratinocytes |
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| 9-80190 | CHI Scientific | 1 x 100 ml | EUR 160.65 |
Krtcap3 (untagged ORF) - Rat similar to keratinocytes associated protein 3 (LOC683980), (10 ug) |
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| RN200835 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF clone of Kprp (mGFP-tagged ORF) - Rat keratinocytes proline-rich protein (Kprp), (10 ug) |
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| RR202226L4 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF clone of Kprp (Myc-DDK-tagged ORF) - Rat keratinocytes proline-rich protein (Kprp), (10 ug) |
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| RR202226L3 | Origene Technologies GmbH | 10 µg | Ask for price |
Krtcap3 (Myc-DDK-tagged ORF) - Rat similar to keratinocytes associated protein 3 (LOC683980), (10 ug) |
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| RR200835 | Origene Technologies GmbH | 10 µg | Ask for price |
HighQC™ Human Keratinocyte Stem Cell |
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| ABC-SC0091 | AcceGen | 1 vial | Ask for price |
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Description: Human Keratinocyte Stem Cell; Frozen Vial and Plated cells are available. Cells are only guaranteed with purchase of Gentaur Media and Gentaur Extra Cellular Matrix for appropriate cell culture, for 30 days from the date of shipment. |
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Lenti ORF particles, Kprp (GFP-tagged ORF) - Rat keratinocytes proline-rich protein (Kprp), 200ul, >10^7 TU/mL |
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| RR202226L4V | Origene Technologies GmbH | 200 µl | Ask for price |
Lenti ORF particles, Kprp (Myc-DDK-tagged ORF) - Rat keratinocytes proline-rich protein (Kprp), 200ul, >10^7 TU/mL |
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| RR202226L3V | Origene Technologies GmbH | 200 µl | Ask for price |
Lenti ORF clone of Krtcap3 (mGFP-tagged ORF) - Rat similar to keratinocytes associated protein 3 (LOC683980), (10 ug) |
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| RR200835L4 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF clone of Krtcap3 (Myc-DDK-tagged ORF) - Rat similar to keratinocytes associated protein 3 (LOC683980), (10 ug) |
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| RR200835L3 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF particles, Krtcap3 (GFP-tagged ORF) - Rat similar to keratinocytes associated protein 3 (LOC683980), 200ul, >10^7 TU/mL |
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| RR200835L4V | Origene Technologies GmbH | 200 µl | Ask for price |
RGD1310352 (untagged ORF) - Rat similar to HTGN29 protein, keratinocytes associated transmembrane protein 2 (RGD1310352), (10 ug) |
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| RN207548 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF particles, Krtcap3 (Myc-DDK-tagged ORF) - Rat similar to keratinocytes associated protein 3 (LOC683980), 200ul, >10^7 TU/mL |
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| RR200835L3V | Origene Technologies GmbH | 200 µl | Ask for price |
Human Keratinocyte Growth Media |
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| MR1013 | celleng-tech | 1 bottle | EUR 216.9 |
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Description: Keratinocyte Growth Media (450mL) |
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RGD1310352 (Myc-DDK-tagged ORF) - Rat similar to HTGN29 protein, keratinocytes associated transmembrane protein 2 (RGD1310352), (10 ug) |
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| RR207548 | Origene Technologies GmbH | 10 µg | Ask for price |
Human Keratinocyte Growth Factor |
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| 90205-A | BPS Bioscience | 2 µg | EUR 130 |
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Description: Recombinant human Keratinocyte Growth Factor is a disulfide-linked monomeric protein consisting of 164 amino acid residues. Optimized DNA sequence encoding Human Keratinocyte Growth Factor mature chain was expressed in E. coli. Native human KGF is generated by the proteolytic removal of the signal peptide and propeptide. KGF migrates as an approximately 19 kDa protein under non-reducing conditions and reducing conditions in SDS-PAGE. |
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Human Keratinocyte Growth Factor |
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| 90205-B | BPS Bioscience | 10 µg | EUR 205 |
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Description: Recombinant human Keratinocyte Growth Factor is a disulfide-linked monomeric protein consisting of 164 amino acid residues. Optimized DNA sequence encoding Human Keratinocyte Growth Factor mature chain was expressed in E. coli. Native human KGF is generated by the proteolytic removal of the signal peptide and propeptide. KGF migrates as an approximately 19 kDa protein under non-reducing conditions and reducing conditions in SDS-PAGE. |
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Human Keratinocyte growth factor (FGF7) |
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| 1-CSB-EP008634HU1 | Cusabio |
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Description: Recombinant Human Keratinocyte growth factor(FGF7),partial expressed in E.coli |
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Human Keratinocyte Expansion Bundle |
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| BR1004 | celleng-tech | n/a | EUR 973.52 |
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Description: Cryopreserved vial of human keratinocyte cells containing ≥ 500,000 cells and Keratinocyte Growth Media (450mL) |
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Lenti ORF clone of RGD1310352 (mGFP-tagged ORF) - Rat similar to HTGN29 protein; keratinocytes associated transmembrane protein 2 (RGD1310352), ( |
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| RR207548L4 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF particles, RGD1310352 (GFP-tagged ORF) - Rat similar to HTGN29 protein; keratinocytes associated transmembrane protein 2 (RGD1310352), |
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| RR207548L4V | Origene Technologies GmbH | 200 µl | Ask for price |
Keratinocyte Growth Factor/FGF-7, His, Human |
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| HY-P7382 | MedChemExpress | 10ug | EUR 321.6 |
Human Keratinocyte growth factor ELISA Kit |
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| MBS289163-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3290 |
Human Keratinocyte growth factor ELISA Kit |
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| MBS289163-48StripWells | MyBiosource | 48-Strip-Wells | EUR 340 |
Human Keratinocyte growth factor ELISA Kit |
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| MBS289163-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1800 |
Human Keratinocyte growth factor ELISA Kit |
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| MBS289163-96StripWells | MyBiosource | 96-Strip-Wells | EUR 435 |
Human Keratinocyte growth factor ELISA Kit |
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| MBS9425916-5x96Tests | MyBiosource | 5x96Tests | EUR 2420 |
Human Keratinocyte growth factor ELISA Kit |
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| MBS9425916-96Tests | MyBiosource | 96Tests | EUR 530 |
Lenti ORF particles, RGD1310352 (Myc-DDK-tagged ORF) - Rat similar to HTGN29 protein; keratinocytes associated transmembrane protein 2 (RGD131035 |
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| RR207548L3V | Origene Technologies GmbH | 200 µl | Ask for price |
Human Keratinocyte Growth Factor,KGF ELISA Kit |
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| 201-12-0152 | Shanghai Sunred Biological Technology | 96 tests | EUR 528 |
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Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
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Human Keratinocyte Growth Factor, KGF ELISA Kit |
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| CSB-E08939h-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
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Description: Quantitativesandwich ELISA kit for measuring Human Keratinocyte Growth Factor, KGF in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Human Keratinocyte Growth Factor,KGF ELISA Kit |
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| CSB-E08939h-48T | Cusabio | 48T | EUR 385.13 |
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Description: Homo sapiens (Human) |
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Human Keratinocyte Growth Factor, KGF ELISA Kit |
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| 1-CSB-E08939h | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Human Keratinocyte Growth Factor, KGF in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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Human Keratinocyte Growth Factor,KGF ELISA Kit |
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| CSB-E08939h-96T | Cusabio | 96T | EUR 592.5 |
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Description: Homo sapiens (Human) |
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Human Keratinocyte Growth Factor,KGF ELISA KIT |
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| E0151Hu-1096T | Jiaxing Korain Biotech Ltd (BT Labs) | 10*96T | EUR 4122 |
Human Keratinocyte Growth Factor,KGF ELISA KIT |
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| E0151Hu-48wells | Jiaxing Korain Biotech Ltd (BT Labs) | 48 wells | EUR 300 |
Human Keratinocyte Growth Factor,KGF ELISA KIT |
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| E0151Hu-596T | Jiaxing Korain Biotech Ltd (BT Labs) | 5*96T | EUR 2061 |
Human Keratinocyte Growth Factor,KGF ELISA KIT |
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| E0151Hu-96wells | Jiaxing Korain Biotech Ltd (BT Labs) | 96 wells | EUR 458 |
Human Keratinocyte Growth Factor(KGF)ELISA Kit |
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| GA-E0168HM-48T | GenAsia Biotech | 48T | EUR 346.8 |
Human Keratinocyte Growth Factor(KGF)ELISA Kit |
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| GA-E0168HM-48Tests | GenAsia Biotech | 48 Tests | Ask for price |
Human Keratinocyte Growth Factor(KGF)ELISA Kit |
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| GA-E0168HM-96T | GenAsia Biotech | 96T | EUR 559.2 |
Human Keratinocyte Growth Factor(KGF)ELISA Kit |
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| GA-E0168HM-96Tests | GenAsia Biotech | 96 Tests | EUR 388 |
Human Keratinocyte Growth Factor(KGF) Elisa Kit |
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| EK711106 | AFG Bioscience LLC | 96 Wells | EUR 0.14 |
Human Keratinocyte Growth Factor(KGF) ELISA Kit |
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| EIA05934h | Enlibio | each | EUR 430 |
Human Keratinocyte Growth Factor,KGF ELISA Kit |
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| EKC40541-48T | Biomatik Corporation | 48T | EUR 597.24 |
Human Keratinocyte Growth Factor,KGF ELISA Kit |
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| EKC40541-5x96T | Biomatik Corporation | 5x96T | EUR 4052.7 |
Observation interval of GFP-labeled epithelial and SEM analysis showed that the extrusion of epithelial appeared in the area in accordance with the fuse region and expanded rostrally on the surface of the nasal septum in the absence of a secondary palatal process. Unlike on the surface of the secondary palate, cell migration and subsequent exposure of mesenchymal autonomous unclear in the nasal septum or palate primer. TUNEL staining revealed that epithelial extrusion undergoing apoptosis. These findings indicate that the extrusion with independent apoptosis begins on the alleged fusion region without contact with the opposing secondary palate.