Viromer® transfection publications

Cytomegalovirus promotes intestinal macrophage-mediated mucosal inflammation through induction of Smad7.

Dennis et. al., Mucosal Immunol., 2018

JNK regulates muscle remodeling via myostatin/SMAD inhibition.

Lessard et. al., Nat Commun. 2018

Ibrutinib blocks Btk-dependent NF-ĸB and NFAT responses in human macrophages during Aspergillus fumigatus phagocytosis.

Bercusson et. al., Blood., 2018

Chromatin Binding of c-REL and p65 Is Not Limiting for Macrophage IL12B Transcription During Immediate Suppression by Ovarian Carcinoma Ascites

Unger et. al., Front. Immunol., 2018

Synthetic mRNA expressed Cas13a mitigates RNA virus infections

Bawage et. al. , BioRxiv, 2018

Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1.

Weber et. al., Nat Commun., 2018

Transition of responsive mechanosensitive elements from focal adhesions to adherens junctions upon epithelial differentiation.

Noethel et. al., Mol Biol Cell., 2018

GATA3 as a master regulator and therapeutic target in ovarian high-grade serous carcinoma stem cells.

Chen et. al., Int J Cancer., 2018

Immunostimulatory guide RNAs mediate potent antiviral response

Cai et. al., BioRxiv, 2018

Membrane Fluidity Is Regulated Cell Non-autonomously by Caenorhabditiselegans PAQR-2 and Its Mammalian Homolog AdipoR2.

Bodhicharla et. al., Genetics., 2018

Neurodevelopmental protein Musashi–1 interacts with the Zika genome and promotes viral replication.

Chavali et. al., Science., 2017

Expression of AGPAT2, an enzyme involved in the glycerophospholipid / triacylglycerol biosynthesis pathway, is directly regulated by HIF-1 and promotes survival and etoposide resistance of cancer cells under hypoxia.

Triantafyllou et. al., Biochim Biophys Acta., 2018

Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.

Ziegler et. al., Cell., 2018

High molecular weight hyaluronic acid: a two-pronged protectant against infection of the urogenital tract?

Mowbray et. al., Clinical & Translational Immunology 2018

Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades.

Li et. al., Oncogene., 201

Apoptotic Cancer Cells Suppress 5-Lipoxygenase in Tumor-Associated Macrophages.

Ringleb et. al., J Immunol., 2018

Recognition of microbial viability via TLR8 drives T_FH cell differentiation and vaccine responses.

Ugolini et.al., Nat Immunol., 2018

The fungal ligand chitin directly binds and signals inflammation dependent on oligomer size and TLR2

Fuchs et. al., BioRxiv, 2018

Novel DNA Aptamers that Bind to Mutant Huntingtin and Modify Its Activity.

Shin et. al., Mol Ther Nucleic Acids., 2018

CRISPR/Cas9 knockout of USP18 enhances type I IFN responsiveness and restricts HIV-1 infection in macrophages.

Taylor et. al., J Leukoc Biol., 2018

The 5T4 oncofetal glycoprotein does not act as a general organizer of the CXCL12 system in cancer cells.

Puchert et. al., Exp Cell Res., 2018

Mechanics-guided embryonic patterning of neuroectoderm tissue from human pluripotent stem cells.

transfections in supplemental data

Xue et. al., Nat Mater., 2018

Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1.

Mueller et. al., J Biol Chem., 2018

Nicotinamide Nucleotide Transhydrogenase as a novel treatment target in adrenocortical carcinoma

Chortis et. al., Endocrinology, 2018

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network.

transfections in supplemental data

Anderson et. al., Nat Commun., 2018

Activation of LANCL2 by BT-11 Ameliorates IBD by Supporting Regulatory T Cell Stability Through Immunometabolic Mechanisms.

Leber et. al., Inflamm Bowel Dis. 2018

Bat lung epithelial cells show greater host species-specific innate resistance than MDCK cells to human and avian influenza viruses.

Slater et. al., Virol J. 2018

Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhimurium infection.

Herrera-Uribe et. al., Vet Res., 2018

Unifying in vitro and in vivo IVT mRNA expression discrepancies in skeletal muscle via mechanotransduction.

Bhosle et. al., Biomaterials. 2018

Involvement of the oncogene B-cell lymphoma 6 in the fusion and differentiation process of trophoblastic cells of the placenta.

Jasmer et. al., Oncotarget., 2017

Functional characterization of the protein kinase MK2 in the pathogenesis of Experimental autoimmune encephalomyelitis (EAE)

Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation.

Mathur et. al., Neuron., 2017

RhoC regulates the actin remodeling required for phagosome formation during FcγR-mediated phagocytosis.

Egami et. al., J Cell Sci., 2017

Systematic Investigation of Multi-TLR Sensing Identifies Regulators of Sustained Gene Activation in Macrophages.

Lin et. al., Cell Syst., 2017

The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty acids

Devkota et. al., PLoS Genet., 2017

Long 3’UTR of Nurr1 mRNAs is targeted by miRNAs in mesencephalic dopamine neurons.

Pereira et. al., PLoS One., 2017

Fatty acid transport protein 1 enhances the macrophage inflammatory response by coupling with ceramide and c-Jun N-terminal kinase signaling.

Nishiyama et. al., Int Immunopharmacol., 2017

Dexamethasone-induced upregulation of CaV3.2 T-type Ca2+ channels in rat cardiac myocytes.

Falcón et. al., J Steroid Biochem Mol Biol., 2017

Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4.

Van Opdenbosch et. al., Cell Rep., 2017

Developmental YAPdeltaC determines adult pathology in a model of spinocerebellar ataxia type 1.

Fujita et. al., Nat Commun., 2017

Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway.

Ambrosio et. al., Oncogene. 2017

Neurochondrin interacts with the SMN protein suggesting a novel mechanism for Spinal Muscular Atrophy pathology.

Thompson et. al., bioRxiv, 2017

Cardiotonic Steroids Stimulate Macrophage Inflammatory Responses Through a Pathway Involving CD36, TLR4, and Na/K-ATPase.

Chen et. al., Arterioscler Thromb Vasc Biol., 2017

The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat

Long et. al., Sci Rep., 2017

E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning.

Rübsam et. al., Nat Commun. 2017

Incorporation of a Ligand Peptide for Immune Inhibitory Receptor LAIR-1 on Biomaterial Surfaces Inhibits Macrophage Inflammatory Responses

Kim et. al., Adv Healthc Mater., 2017

FGF23 activates injury-primed renal fibroblasts via FGFR4-dependent signalling and enhancement of TGF-β autoinduction

Smith et. al., Int J Biochem Cell Biol., 2017

The MAV_4644 dual-function channel protein with putative ADP-ribosyltransferase activity of Mycobacterium avium is required for virulence within host macrophages

Lewis – 2017

METHYL CAP BINDING PROTEIN 2 IN SYSTEMIC SCLEROSIS

O’Reilly – 2017

Enhancer of rudimentary homologue interacts with scaffold attachment factor B at the nuclear matrix to regulate SR protein phosphorylation.

Drakouli et. al., FEBS J., 2017

Targeting Deficiencies in the TLR5 Mediated Vaginal Response to Treat Female Recurrent Urinary Tract Infection.

The scaffold protein Ajuba suppresses CdGAP activity in epithelia to maintain stable cell-cell contacts.

McCormack et. al., Sci Rep., 2017

CHARACTERIZATION OF IN VITRO TRANSCRIBED MRNA FOR OPTIMAL EXPRESSION IN THERAPEUTIC APPLICATIONS

The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability.

Shah et. al., Nat Commun., 2017

Caffeine induces gastric acid secretion via bitter taste signaling in gastric parietal cells

Liszt et. al., Proc Natl Acad Sci U S A., 2017

Angiopoietin-like Protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP

Ingerslev et. al., Mol Metab., 2017

Integrated analysis of miRNA expression in response to Salmonella  Typhimurium infection in pigs.

Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6.

Brüser et. al., Sci Rep., 2017

The embryonic type of SPP1 transcriptional regulation is re-activated in glioblastoma.

Kijewska et. al., Oncotarget., 2017

Live cell imaging of mitochondria following targeted irradiation in situ reveals rapid and highly localized loss of membrane potential.

Walsh et. al., Sci Rep., 2017

Characterizing exogenous mRNA delivery, trafficking, cytoplasmic release and RNA-protein correlations at the level of single cells.

Kirschman et.al., Nucleic Acids Res., 2017

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.

Armento et. al., Int J Oncol., 2017

Hmga2 translocation induced in skin tumorigenesis.

Li et. al., Oncotarget., 2017

FGF23 is synthesised locally by renal tubules and activates injury–primed fibroblasts.

transfections in supplemental data

Smith et. al., Sci Rep., 2017

The role of microRNA-5196 in the pathogenesis of systemic sclerosis.

Ciechomska et. al., Eur J Clin Invest., 2017

Effects of hypnotic bromovalerylurea on microglial BV2 cells.

Kawasaki et. al., J Pharmacol Sci., 2017

HCMV activation of ERK-MAPK drives a multi-factorial response promoting the survival of infected myeloid progenitors.

Kew et. al., J Mol Biochem., 2017

Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.

Furtado et. al., JCI Insight., 2017

A p110δ-specific inhibitor combined with bortezomib blocks drug resistance properties of EBV-related B cell origin cancer cells via regulation of NF-κB.

Park et. al., Int J Oncol., 2017

Corneal stromal stem cells reduce corneal scarring by mediating neutrophil infiltration after wounding.

Hertsenberg et. al., PLoS ONE, 2017

GANCICLOVIR DERIVATIVES FOR MODULATING INNATE AND ADAPTIVE IMMUNITY AND FOR USE IN IMMUNOTHERAPY

Burai et. al., US Patent 20,170,050,967, 2017

Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity.

Czirr et. al., J Exp Med., 2017

The RNA-binding protein Tristetraprolin (TTP) is a critical negative regulator of the NLRP3 inflammasome.

Haneklaus et. al., JBC, 2017

Macrophage inducible C-type lectin (Mincle) recognizes glycosylated surface (S)-layer of the periodontal pathogen Tannerella forsythia.

Chinthamani et. al., PLoS ONE, 2017

IKKα controls ATG16L1 degradation to prevent ER stress during inflammation.

Diamanti et. al., J Exp Med., 2017

Downregulation of Lnc-Spry1 mediates TGF-β-induced epithelial–mesenchymal transition by transcriptional and posttranscriptional regulatory mechanisms.

Rodríguez-Mateo et. al., Cell Death & Differentiation, 2017

Single α-particle irradiation permits real-time visualization of RNF8 accumulation at DNA damaged sites.

Muggiolu et. al., Sci Rep., 2017

The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma.

Mescher et. al., J Exp Med.,  2017

The dual role of asporin in breast cancer progression.

Simkova et.al., Oncotarget., 2016

Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures.

Morrison et.al., J. Vis. Exp., 2016

Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability.

Hadadi et.al., Sci Rep.,  2016

The p7 viroporin of the hepatitis C virus contributes to liver inflammation by stimulating production of Interleukin-1 β.

Farag et. al., Biochim Biophys Acta., 2016

Loss of the Tumor Suppressor NKX3.1 in Prostate Cancer Cells is Induced by Prostatitis Related Mitogens

Decker et.al., J Clin Onc Exp Onc, 2016

MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity.

Salama et. al., PLoS One, 2014

Vernakalant activates human cardiac K(2P)17.1 background K(+) channels.

Seyler et. al., Biochem Bophys Res Commun., 2014

Post-transcriptional regulation of BCL2 mRNA by the RNA-binding protein ZFP36L1 in malignant B cells.

Zekavati et. al., PLoS One, 2014

Time-resolved quantitative proteomics implicates the core snRNP protein SmB together with SMN in neural trafficking.

Prescott et. al., J Cell Sci., 2014

High-Tech Polymers Leveraging Viral Biophysics Can Enhance the Transfection of Nucleic Acids

Panzner, GEN, 2014