Viromer® IN VIVO is a strong and powerful, polymer based in vivo transfection reagent, that provides excellent performance by delivering mRNA safe and efficient into animal models.
Rapid and durable transfection of luciferase mRNA into spleen.
10μg mRNA formulated using specific Viromer®,mice seen from dorsal side.
Signal appears as early as 2h after tail vein injection…
…peaks at 6h and…
…expressed protein is still active after 44h.
Rapid and strong transfection of luciferase mRNA into liver.
Using 25 or 40μg of the mRNA:Viromer® complex, a preferred liver targeting is achieved. Expression in liver is very pronounced after 6h and still detectable after 24h.