monocyte transfection

siRNA / miRNA transfection into primary monocytes:

Cytomegalovirus promotes intestinal macrophage-mediated mucosal inflammation through induction of Smad7.

Dennis et. al., Mucosal Immunol., 2018

Recognition of microbial viability via TLR8 drives TFH cell differentiation and vaccine responses.

Ugolini et.al., Nat Immunol., 2018

The role of microRNA-5196 in the pathogenesis of systemic sclerosis.

Ciechomska et. al., Eur J Clin Invest., 2017

Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability.

Hadadi et.al., Sci Rep.,  2016

Histone demethylation and TLR8-dependent crosstalk in monocytes promotes trans-differentiation of fibroblasts in systemic sclerosis via Fra2.

Ciechomska et.al., Arthritis Rheumatol, 2016

siRNA / miRNA transfection into THP-1 monocytes:

The MAV_4644 dual-function channel protein with putative ADP-ribosyltransferase activity of Mycobacterium avium is required for virulence within host macrophages

Lewis – 2017

The RNA-binding protein Tristetraprolin (TTP) is a critical negative regulator of the NLRP3 inflammasome.

Haneklaus et. al., JBC, 2017

Macrophage inducible C-type lectin (Mincle) recognizes glycosylated surface (S)-layer of the periodontal pathogen Tannerella forsythia.

Chinthamani et. al., PLoS ONE, 2017

Implications of a genetically determined nitric oxide deficit for endothelial cell-leukocyte interaction and cardiovascular disease

Kadiyska – 2016

siRNA / miRNA transfection into U-937 monocytes:

The role of microRNA-5196 in the pathogenesis of systemic sclerosis.

Ciechomska et. al., Eur J Clin Invest., 2017

plasmid transfection into THP-1 monocytes:

The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat

Long et. al., Sci Rep., 2017

gRNA transfection into THP-1 monocytes:

Immunostimulatory guide RNAs mediate potent antiviral response

Cai et. al., BioRxiv, 2018