monocyte transfection

siRNA / miRNA transfection into primary monocytes:

Recognition of microbial viability via TLR8 drives TFH cell differentiation and vaccine responses.

Ugolini et.al., Nat Immunol., 2018

The role of microRNA-5196 in the pathogenesis of systemic sclerosis.

Ciechomska et. al., Eur J Clin Invest., 2017

Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability.

Hadadi et.al., Sci Rep.,  2016

Histone demethylation and TLR8-dependent crosstalk in monocytes promotes trans-differentiation of fibroblasts in systemic sclerosis via Fra2.

Ciechomska et.al., Arthritis Rheumatol, 2016

siRNA / miRNA transfection into THP-1 monocytes:

The MAV_4644 dual-function channel protein with putative ADP-ribosyltransferase activity of Mycobacterium avium is required for virulence within host macrophages

Lewis – 2017

The RNA-binding protein Tristetraprolin (TTP) is a critical negative regulator of the NLRP3 inflammasome.

Haneklaus et. al., JBC, 2017

Macrophage inducible C-type lectin (Mincle) recognizes glycosylated surface (S)-layer of the periodontal pathogen Tannerella forsythia.

Chinthamani et. al., PLoS ONE, 2017

Implications of a genetically determined nitric oxide deficit for endothelial cell-leukocyte interaction and cardiovascular disease

Kadiyska – 2016

siRNA / miRNA transfection into U-937 monocytes:

The role of microRNA-5196 in the pathogenesis of systemic sclerosis.

Ciechomska et. al., Eur J Clin Invest., 2017

plasmid transfection into THP-1 monocytes:

The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat

Long et. al., Sci Rep., 2017